HIV therapeutic vaccine enhances non-exhausted CD4+ T cells in a randomised phase 2 trial
نویسندگان
چکیده
منابع مشابه
CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection
OBJECTIVE HIV type 2 (HIV-2) represents an attenuated form of HIV, in which many infected individuals remain 'aviremic' without antiretroviral therapy. However, aviremic HIV-2 disease progression exists, and in the current study, we therefore aimed to examine if specific pathological characteristics of CD4 T cells are linked to such outcome. DESIGN HIV-seronegative (n = 25), HIV type 1 (HIV-1...
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ژورنال
عنوان ژورنال: npj Vaccines
سال: 2019
ISSN: 2059-0105
DOI: 10.1038/s41541-019-0117-5